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® Uniquely designed to lift and tighten the skin on the face† and deliver and abdomen*, Ultherapy PRIME® visualization, with the power to see clearly and reach deep. Personalized‡ to each patient’s unique anatomy, all in one session, with zero downtime. Suitable for all skin tones. Now for face† and body*.1,3 The future of beauty is here. Ultherapy PRIME CAN SEE® †Face refers to cleared indications for Ultherapy PRIME®. *Indicated to improve the appearance of skin laxity on the abdomen, anterior arms and posterior arms. 2 Actual patient - posterior arms not treated. Individual results may vary.
Discover Ultherapy PRIME®, the advanced ultrasound platform indicated to lift and tighten the upper face, lower face, neck and décolleté and improve the appearance of skin laxity on the anterior and posterior arms and abdomen.1 ADVANCED TECHNOLOGY: VIVID REAL-TIME VISUALIZATION: ® 7 ‡‡ PROVEN RESULTS: ‡ †† **Average reported increase in system speed over legacy Ultherapy® device based on a survey of providers. ‡Personalizing means use of real-time visualization ‡‡Compared to legacy Ultherapy®. ††Ultherapy PRIME® results can last up to 6 months for the arms and abdomen and up to a year or more in the face†. 3
ADVANCED ® ADVANCED PLATFORM features 20% faster treatments* Elevated ergonomics A sophisticated design Greater patient comfort7 of the ultrasound imaging due to new, powerful system components time to commands from power on to use readiness vs. legacy Ultherapy® , paired with a new operating system and modern drivers, to enable future software innovations *Average reported increase in system speed over legacy Ultherapy® device based on a survey of providers. 4
to meet the needs of modern aesthetics practices viewing angles for optimal capacitive touchscreen to keep treatment equipment in place for easy interaction with the device better treatment experience for a ® comfort, with average pain scores less than half those of legacy Ultherapy®7
Assess each patient’s anatomical needs Choose appropriate transducer depth Ensure optimal coupling to promote safer treatments Deliver energy for truly personalized‡ results that Improve patient comfort with visualized tissue targeting *Ultherapy PRIME® results can last up to 6 months for the arms and abdomen and up to a year or more in the face. Face refers to cleared indications for Ultherapy PRIME®. †Compared to legacy Ultherapy® .‡Personalizing means use of real-time visualization. 6
® The platform stands out with distinct attributes to elevate your visualization experience.1,6 vs. legacy Ultherapy® down to 8mm depth6 † screen † Human avatar with 7
Ultherapy PRIME® harnesses the power of energy to lift and tighten the skin on the face* and improve skin laxity on the arms and abdomen:†,1 Stimulates tissue layers rich in collagen and elastin without damaging the skin’s surface and elastin denaturation and synthesis1,3,4,11,13 younger looking skin THE REGENERATIVE PROCESS During the initial phase, macrophages engulf and digest injured tissue and release synthesize the newly created type III collagen alongside other mediators important to rebuilding the collagen matrix.12,13,17 In the maturation and remodeling sustained results. Artist’s renderings are for illustrative purposes only. 8
Ultherapy PRIME® 1, 18,19 26% increase in collagen Type I 42% increase in production of collagen vs untreated skin12 66% increase in skin thickness for improved skin quality13 ® is a category leader and incorporates the latest innovations and technologies. It is the evolution of Ultherapy®, aesthetic physicians.3,4 *Face refers to cleared indications for Ultherapy PRIME®. **Ultherapy PRIME® results can last up to 6 months for the arms and abdomen and up to a year or more in the face.* †Indicated to improve the appearance of skin laxity on the abdomen, anterior arms and posterior arms. 9
GET PERSONAL, . See proven results with Ultherapy PRIME® , intended for dermis of the upper face, lower face, neck and décolleté3 and for improved laxity on the arms and abdomen.†,1 Personalize* each treatment to your patient’s unique needs in one session with zero downtime to deliver a sustained lift for all skin tones that lasts up to a year or more.**,3,4 S Y A D 0 5 4 R E T F A S Y A D 0 8 1 R E T F A S Y A D 0 9 R E T F A E R O F E B E R O F E B E R O F E B S Y A D 0 7 R E T F A S Y A D 0 9 R E T F A S Y A D 0 8 1 R E T F A E R O F E B E R O F E B E R O F E B Actual Ultherapy® patients. Individual results may vary. *Personalizing means use of real-time visualization. **Ultherapy PRIME® results can last up to 6 months for the arms and abdomen and up to a year or more in the face. Face refers to cleared indications for Ultherapy PRIME®. †Indicated to improve the appearance of skin laxity on the abdomen, anterior arms and posterior arms. 10
FOR FIRMER, MORE TONED SKIN ON THE E R O F E B E R O F E B E R O F E B Actual patient, posterior arms not treated - Individual results may vary. *Indicated to improve the appearance of skin laxity on the abdomen, anterior arms and posterior arms. 12 S Y A D 0 9 R E T F A S Y A D 0 9 R E T F A S Y A D 0 9 R E T F A
building on a legacy of a 95% patient satisfaction rate at year 1, over 3.5 million treatments* in more than 80 countries worldwide, and the strongest clinical body of evidence 3,18,20 to a unique platform today and in the future. Ask your sales representative about Ultherapy PRIME – The Lift You Can SEE®. The Ulthera® dermatological sculpting and lifting of the dermis of the upper face, lower face, neck and décolleté, and to improve the appearance of skin laxity on the abdomen, anterior arms, and posterior arms. *Performed with Legacy Ultherapy® and Ultherapy PRIME® 1. Ulthera® Instructions for Use. 2. Vasanop Vachiramon, MD, Korn Triyangkulsri, MD, Wimolsiri Iamsumang, MD, MSc, and Pamela Chayavichitsilp, MD Division of Dermatology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, 10400, Thailand. 10. Alster TS, Tanzi EL. Noninvasive lifting of arm, thigh, and knee skin with transcutaneous intense focused 11. Pavicic T, Ballard JR, Bykovskaya T, et al. Microfocused ultrasound with visualization: Consensus on safety and review of energybased devices. J Cosmet Dermatol. 2021. 12. Sasaki G, Grossman J, Fabi SG, et al. Stimulation of Collagen Synthesis in Human Skin Following Microfocused Ultrasound Therapy. Presented at the ASDS 2018 Annual Meeting. 13. With Visualization in theTreatment of Upper Arm Skin intensity focused ultrasound and radiofrequency on skin. J Lasers in Surgery and Medicine. 3. Fabi SG, Joseph J, Sevi J, Green JB, Peterson JD. Optimizing patient outcomes by customizing treatment with microfocused ultrasound with visualization: gold standard consensus guidelines from an expert panel. J 14. Fabi SG, Massaki A, Eimpunth S, Pogoda J, Goldman MP. Evaluation of microfocused ultrasound with visualization for lifting, tightening, and wrinkle reduction of the Guo S, Dipietro LA. Factors affecting wound 4. Ultrasound with Visualization for Optimized Patient Outcomes: A Review of Skintightening Energy Panel’s Gold Standard Consensus. J Clin Aesthet Dermatol. Vachiramon V, Triyangkulsri K, Iamsumang W, ultrasound with visualization in abdominal skin laxity: A randomized, comparative study. Lasers Surg Med. 6. Levine J, McCarthy AD, Pavicic T, et al. Comparative Ultrasound Visualization Analysis Between Ultherapy® and Ultherapy PRIME® and Survey and Clinical Case Results from the Ultherapy PRIME® Early Experience Program. 2024. Data on File. 7. Panithaporn D. Pain, Erythema, and Edema After Facial Lifting With Ultherapy Prime or Ultherapy® 8. Marquardt K, Hartmann C, Wegener F, et al. Microfocused ultrasound with visualization induces remodeling of collagen and elastin within the skin. J Cosmet Dermatol. 9. Lin F, Nonsurgical Treatment of Postpartum Lower Microfocused Ultrasound With Visualization. Amer Soc for Derm Surg., Published by Wolters Kluwer Health, Inc. 20139336; PMCID: PMC2903966 16. Hirayama D, Iida T, Nakase H. The Phagocytic Function 17. Fabi SG. Noninvasive skin tightening: focus on new ultrasound techniques. Clin Cosmet Investig Dermatol. 18. tightening lax facial and neck skin using a customized vectoring treatment method. J Clin Aesthet Dermatol. 19. Meyer PF, Meleck M, Borges F dos S et al. Effect of Microfocused Ultrasound on Facial Rejuvenation: Clinical 20. ©2026 Merz Aesthetics GmbH. All Rights Reserved. MERZ