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MERZ AESTHETICS® celebrates the unqueness n you and your patents. Together, we help the world look better, feel better, and lve better. Changng the world together: Merz Aesthetcs® has establshed a reputaton as a relable ndustry partner to health care profes- sonals around the world. For our partners and for us, aesthetc medcne s much more than optmzng appearance. At ts core s the beauty that only emerges wth a sense of confidence, unqueness and self-assurance. We exst to fuel confidence n every person we touch – confidence n self and confidence n us. We are poneerng the ndustry wth the way we see beauty n unqueness and celebrate orgnalty. We empower ndvduals n ther personal quests to be ther best selves – no matter what that means. Because every person has a unque brand of confidence. 3
Our Story 1908 Chemst and pharmacst Fredrch Merz founded hs own pharmaceutcal producton faclty n Frankfurt am Man. Over 115 years of innovation, dedication, and trust. 4 MERZ AESTHETICS®
The Merz Aesthetcs Heritage The Merz Group has been a successful German healthcare company for over 115 years. Founded n 1908 n Frankfurt by 23-year-old chemst Fredrch Merz, the company has grown steadly over the decades. In 2020, Merz underwent a strategc transformaton, restructurng nto three customer-focused busnesses: Merz Aesthetcs, Merz Therapeutcs, and Merz Lfecare. Ths new structure enables the needs of customers and patents, accelerate nnovaton cycles, and seze market opportuntes wth greater precson. Merz Aesthetcs s located n Ralegh, North Carolna, USA—at the heart of one of the world’s largest and fastest-growng markets. The EMEA Regonal Team s based n Frankfurt am Man, where Merz was orgnally founded. From ths vbrant hub, the team drves strategy and collaboraton across Europe, the Mddle East, and Afrca, brngng nnovaton and excellence to the regon. HERITAGE 5
Rooted n Legacy, Growng Toward Tomorrow 2014 Introducton of mcrofocused ultrasound technology nto the Merz Aesthetcs portfolo 2011 Frst Merz expert meetng held 2010 Calcum hydroxylapatte added to the product portfolo n Germany Frst branch establshed n Asa and the Pacfic regon 1908 Merz Pharmaceutcals founded by Fredrch Merz 1911 Patentax topcal contraceptve 1930 Frst nternatonal branches establshed n the Unted States and the Unted Kngdom 1953 Frst ant- wrnkle cream 1964 Launch of Merz Spezal Dragées 2005 Merz enters the field of aesthetc medcne Launch of the hyaluronc acd filler 6 MERZ AESTHETICS®
MERZ AESTHETICS® 2024 A new chapter n non-nvasve lftng begns. 2020 Establshment of a dedcated global organzatonal structure 2019 Introducton of the beauty booster for skn revtalzaton ® 2018 Launch of the Fller-Duo for enhancng the lps HISTORY 7
Advancng scence n medcal aesthetcs. Together. The health and well-beng of your patents are at the heart of everythng we do every day. All Merz Aesthetcs products comply wth hgh standard of safety requrements and defined qualty measurement processes. Patent safety mportant values our research and Development Reducton of fine lnes, rejuvenaton, tghtenng, contourng, and volume enhancement: supported by a large number of clncal studes and scentfic publcatons, our extensve product portfolo s settng new standards n scence-based aesthetc medcne – delverng trusted results. 8 MERZ AESTHETICS®
More Confidence Worldwde 15 000 Voces, 1 Message In 2025, Merz Aesthetcs unvels the findngs of ts global survey, Pllars of Confidence, conducted across 15 countres. The survey explores how people today define self-confidence and the role physcal appearance plays n shapng t. As part of the ‘Confidence To Be’ ntatve, we partnered wth Ipsos to conduct a global survey of 15,000 ndvduals aged 21 to 75 across 15 countres, all of whom have ether experenced or are open to explorng aesthetc treatments. 72% of respondents agree wth the statement: “I am confident and I know who I am.” 1 73% of respondents report feelng “empowered” after a treatment.1 69% of respondents want aesthetc procedures to make ther nner feelngs vsble on the outsde.1 72% of respondents say that such treatments nfluence ther self-percepton.1 PILLARS OF CONFIDENCE 11
What we learned about confidence. 1. Redefinng Confidence Confidence s more than a feelng—t’s an expresson of well-beng, reslence, and personal growth. Those who feel comfortable n ther own bodes move through lfe wth greater confidence. Aesthetc treatments can make 2. Treatments as Self-Care For many, aesthetc procedures are no longer a luxury, but part of a regular care routne. They help express one’s true self and foster a sense of empowerment n everyday lfe. For more self-confidence—worldwde. 3. Between Openness and Judgment More and more people are engagng openly wth the topc, yet fear of socal judgment perssts. Close relatonshps shape self-mage more than meda or socetal norms. At the same tme, socal meda and nfluencers are ganng mportance—they nform, nspre, and normalze. 12 MERZ AESTHETICS®
Merz Aesthetcs - Product Portfolio An ntentonally desgned, comprehensve collecton of hghly cohesve hyaluronc acd (HA) fillers delverng predctable and natural-lookng results through seamless tssue ntegraton. 2 Belotero treats varous ndcatons, from fine lnes and wrnkles to volume enhancement. 3 More than 10 mllon patents treated globally. 10 16 MERZ AESTHETICS®
RADIESSE® s a hghly researched and extensvely studed regeneratve bostmulator for skn qualty. It utlzes nnovatve partcle technology whch actvates the body’s regeneratve potental to firm and tghten your skn and reverses vsble sgns of ageng from wthn. 4 More than 11 Mllon patents treated globally. 10 The only advanced mcro-focused ultrasound platform wth vvd, ntegrated real-tme vsualzaton unquely desgned to non-nvasvely lft and tghten the skn on the face† and delver frmer, more toned skn on the arms and abdomen* 5-9 Personalzed‡ to each patent’s unque anatomy for long-lastng** results, all n one sesson, wth zero downtme. Sutable for all skn tones. Now for face† and body*.5,7 † Face refers to cleared ndcatons for Ultherapy PRIME®. * Indcated to mprove the appearance of skn laxty on the abdomen, anteror arms and posteror arms. ‡ Personalzng means use of real-tme vsualzaton ** Ultherapy PRIME® results can last up to 6 months for the arms and abdomen* and up to a year or more n the face. Face refers to cleared ndcatons for Ultherapy PRIME®. MERZ AESTHETICS® PORTFOLIO 17
Your Unfied Gateway To Aesthetcs Excellence MAX Merz Aesthetcs Exchange, s more than just a servce platform – t’s the umbrella that brngs together Desgned to support your professonal journey, MAX unfies all servce categores nto a seamless experence talored to your needs. Whether you’re engagng wth us onlne, through personalzed learnng formats or at a congress, MAX ensures that every nteracton s consstent, hgh qualty, and focused on your growth. From product specfic-servces, knowledge growth, and practce success support, MAX s your trusted partner n stayng ahead n the ever-evolvng field of aesthetcs. Wth MAX, you don’t just access servces – you become part of a connected, forward-thnkng communty dedcated to excellence n aesthetc medcne. Master our products. Complement your skillset. Grow your practice. I want to learn more about I want to enhance my I want to elevate my clnc’s a specfic Merz Aesthetcs knowledge and skllset wthn performance and grow the product. the aesthetcs area. busness. Ask your Merz Aesthetcs® representatve for more nformaton on the MAX Merz Aesthetcs Exchange platform. 18 MERZ AESTHETICS®
References Pllars of Confidence RADIESSE® 1 © Merz Aesthetcs. (2025). Pllars of Confidence: Global Insghts on 4 Km J et al., Cln. Cosmet. Investg. Dermatol. 2019; 12: 771–784. 2024 and October 8, 2024 Product Portfolo BELOTERO® 2 Mcheels et al. J Cln AesthetDermatol. 2017;10(1):29-36 Black et al. Dermatologc Surgery. 2018 Jul 1;44(7):1002-11 Vandeputte et al. The Journal of Clncal and Aesthetc Dermatology. 2018;11(12):30 3 BELOTERO® Revve. Instructons For Use (IFU 2025, EU). BELOTERO® Balance Ldocane. Instructons For Use (IFU 2025, EU). BELOTERO® Intense Ldocane. Instructons For Use (IFU 2025, EU) BELOTERO® Volume Ldocane. Instructons For Use (IFU 2025, EU). BELOTERO® Soft Ldocane. Instructons For Use (IFU 2025, EU) ULTHERAPY® 5 Ulthera® Instructons for Use. 6 Vasanop Vachramon, MD, Korn Tryangkulsr, MD, Wmolsr Iamsumang, MD, MSc, and Pamela Chayavchtslp, MD Dvson of Dermatology, Faculty of Medcne Ramathbod Hosptal, Mahdol Unversty, Bangkok, 10400, Thaland. Sngle‐Plane Versus Dual‐Plane Mcrofocused Ultrasound Wth Vsualzaton n theTreatment of Upper Arm Skn Laxty: A Randomzed, Sngle‐Blnded, Controlled Tral. Lasers n Surgery and Medcne. 7 Fab SG, Joseph J, Sev J, Green JB, Peterson JD. Optmzng patent outcomes by customzng treatment wth mcrofocused ultrasound wth vsualzaton: gold standard consensus gudelnes from an expert panel. J Drugs Dermatol. 2019;18(5):426-432. 8 Park JY, et al. Customzed Treatment Usng Mcrofocused Ultrasound wth Vsualzaton for Optmzed Patent Outcomes: A Revew of Skntghtenng Energy Technologes and a Pan-Asan Adaptaton of the Expert Panel’s Gold Standard Consensus. J Cln Aesthet Dermatol. 2021;14(5):E70-E79. 9 Vachramon V, Tryangkulsr K, Iamsumang W, Chayavchtslp P. Effcacy and safety of mcrofocused ultrasound wth vsualzaton n abdomnal skn laxty: A randomzed, comparatve study. Lasers Surg Med. 2020;52(10):825-832. do:10.1002/lsm.23234. For detaled product nformaton please refer to the product nstructons for use or reach out to your Merz Aesthetcs representatve. REFERENCES 19
MERZ AESTHETICS® empowers people to confidently express ther unque atttude. We help them to look better, feel better, lve better. merzaesthetcs.com | merzaesthetcs ©2026 Merz Aesthetcs GmbH. MERZ, MERZ AESTHETICS®, MAX Merz Aesthetcs Exchange, and BELOTERO® are trademarks and/or regstered trademarks of Merz Pharma GmbH & Co. KGaA n the EU and/or certan other countres. RADIESSE® s a trademark and/or regstered trademark of Merz North Amerca, Inc. n the EU and/or certan other countres. ULTHERAPY® s a trademark and/or regstered trademark of Ulthera, Inc. n the EU and/or certan other countres. All other trademarks and/or regstered trademarks are the property of ther respectve owners.