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THE POWER OF PERSONALIZED, LONGLASTING RESULTS*. *can last a year or more3,4
SEE THE DIFFERENCE WITH ULTHERAPY PRIME®. ADVANCED Ultherapy PRIME® is an advanced platform with a faster and more powerful processing performance*, a sophisticated design with elevated ergonomics, and vivid, real-time visualization that enables you to truly personalize your treatments to your patients’ unique features, all supported by a strong legacy of proven results you know and trust.1, 13, 14 SOPHISTICATED-LOOKING PLATFORM to meet the needs of modern aesthetic practices TILTABLE SCREEN for optimal viewing angles LARGE 19-INCH, HIGH-RESOLUTION, capacitive touchscreen INTEGRATED WORK SUR- FACE to keep treatment equipment in place ERGONOMICALLY ANGLED CART PLATFORM for easy interaction with the device QUIET SYSTEM SOUNDS for a better treatment experience
FASTER REFRESH RATE of the ultrasound imaging due to new powerful system components* INSTANT RESPONSE time to commands 20% FASTER PLATFORM* NEARLY TWICE AS FAST BOOT-UP TIME from power on to use readiness* IMPROVED STABILITY AND MEMORY MANAGEMENT paired with a new operating system and modern drivers to enable future software innovations *in comparison to the Ultherapy® legacy device
THE LIFT YOU CAN SEE®. VIVID The Ultherapy PRIME® platform stands out with distinct attributes to elevate your visualization experience. Compared to the original Ultherapy®, which has a 15-inch screen and a 7-inch ultrasound panel, Ultherapy PRIME® now features a 35% larger screen, now 19 inches, and a twice-as-large ultrasound field, now 10 inches. 35% LARGER screen* 2X LARGER ultrasound field* REDUCED VISUAL NOISE FOR STABLE, CLEAR IMAGING up to 8mm deep* EASY-TO-USE GRAPHICAL USER INTERFACE for intuitive workflows Human avatar with MODERN, PATIENTRESEMBLING APPEAL *in comparison to the Ultherapy® legacy device - -
Ultherapy PRIME® is the only non-invasive ultrasound treatment with real-time visualization that lifts the neck, under the chin, and brow and improves lines and wrinkles on the décolleté.3 Its unique imaging technology allows you to see your patients’ anatomy in real time so you can assess their individual needs and personalize each treatment, creating optimized outcomes.1, 3, 13, 14 Real-time visualization is essential to promote safer and more effective treatments.1, 3, 13, 14 Assess each patient’s anatomical needs. Choose appropriate transducer depths. Ensure optimal coupling to promote safer treatments. Deliver energy into specific tissue targets for a truly personalized lift. Improve patient comfort with visualized tissue targeting.
THE POWER OF UNIQUE TECHNOLOGY. THE REGENERATIVE PROCESS PROVEN Ultherapy PRIME® is the only microfocused ultrasound treatment with integrated real-time visualization that creates thermal coagulation points (TCPs) at the precise depths of 1.5, 3.0, and 4.5mm to reach the collagen- and elastin-rich tissue layers without damaging the skin’s surface.2, 5, 6 Its engineering precision promotes an accurate delivery of TCPs at optimal, consistent coagulative temperatures of 60–70°C, initiating collagen denaturation and synthesis for effective, reproducible results.1, 2, 3, 13, 14 PHASE 1: TEMPORARY INFLAMMATION ASSOCIATED WITH THE HEALING PROCESS During the initial phase, macrophages engulf and digest injured tissue and release cytokines, which attract fibroblasts.2, 6, 15-17 PHASE 2: PROLIFERATION In the proliferation phase, fibroblasts synthesize the newly created type III collagen alongside other mediators important to rebuilding the collagen matrix.2, 6, 15 PHASE 3: MATURATION & REMODELING In the maturation and remodeling phase, type III collagen is replaced by type I collagen, forming tight cross-links with itself and other proteins, leading to “a long-term, sustained lifting and tightening result that can last up to a year or more. Artist’s renderings are for illustrative purposes only.
GET PERSONAL, GET RESULTS. See proven results with Ultherapy PRIME®, indicated for non-invasive lifting of the brow, under the chin, neck, and improvement of lines and wrinkles on the décolleté.3 Personalize each treatment to your patient’s unique needs with zero downtime to create a sustained lift for all skin tones that can last a year or more.3, 4 E R O F E B E R O F E B E R O F E B S Y A D 0 7 R E T F A S Y A D 0 9 R E T F A S Y A D 0 8 1 R E T F A E R O F E B E R O F E B E R O F E B S Y A D 0 5 4 R E T F A S Y A D 0 8 1 R E T F A S Y A D 0 9 R E T F A Actual Ultherapy® patients. Individual results may vary. Your personalized lift that can last a year or more.3, 4 One session. Zero downtime. For all skin tones.
Uplift your practice with the evolution of the Gold Standard in non-invasive lifting, building on a legacy of a 95% patient satisfaction rate at year 1, over 2.5M treatments in more than 80 countries worldwide, and a strong clinical body of evidence, with over 100 publications and 56 clinical studies.4, 11, 12 See desirable outcomes, elevated ergonomics, and fast, seamless workflows that add up to a smart investment in a unique platform today and into the future. Ask your sales representative about Ultherapy PRIME – The Lift You Can SEE®. Ultherapy PRIME® System is indicated to lift skin on the neck, on the 9. Data on File ASL. eyebrow, and under the chin, as well as to improve lines and wrinkles on the 10. Data on File. Devices shipped globally. décolleté. Reported adverse events from post-marketing surveillance are 11. available in the Instructions for Use (IFU). Data on File. Ultherapy® Ultrasound or Skin Lifting and Tightening Literature Search Jan 2023. 12. Data on File. Please reference the IFU for additional information, including specific 13. Pavicic T, Ballard JR, Bykovskaya T, et al. Microfocused ultrasound with indications in your country, full product and safety information, and possible visualization: Consensus on safety and review of energy-based devices. side effects. J Cosmet Dermatol. 2021. 14. Park JY, et al. Customized Treatment Using Microfocused Ultrasound 1. Fabi SG, Joseph J, Sevi J, Green JB, Peterson JD. Optimizing patient with Visualization for Optimized Patient Outcomes: A Review of outcomes by customizing treatment with microfocused ultrasound Skintightening Energy Technologies and a Pan-Asian Adaptation of with visualization: gold standard consensus guidelines from an expert the Expert Panel’s Gold Standard Consensus. J Clin. Aesthet Dermatol. panel. J Drugs Dermatol. 2019;18(5):426-432. 2021;14(5):E70-E79. 2. Suh DH, Choi JH, Lee SJ, Jeong KH, Song KY, Shin MK. Comparative 15. Fabi SG. Noninvasive skin tightening: focus on new ultrasound histometric analysis of the effects of high-intensity focused ultrasound techniques. Clin Cosmet Investig Dermatol. 2015 Feb 5;8:47-52. doi: and radiofrequency on skin. J Cosmet Laser Ther. 2015;17(5):230-236. Ulthera® Instructions for Use. 3. 10.2147/CCID.S69118. PMID: 25709486; PMCID: PMC4327394. 16. Guo S, Dipietro LA. Factors affecting wound healing. J Dent Res. 2010 4. Werschler WP, Werschler PS. Longterm efficacy of micro-focused Mar;89(3):219-29. doi: 10.1177/0022034509359125. Epub 2010 Feb 5. PMID: ultrasound with visualization for lifting and tightening lax facial and 20139336; PMCID: PMC2903966 neck skin using a customized vectoring treatment method. J Clin 17. Hirayama D, Iida T, Nakase H. The Phagocytic Function of Aesthet Dermatol. 2016;9(2):27-33. Macrophage-Enforcing Innate Immunity and Tissue Homeostasis. Int 5. Fabi SG, Massaki A, Eimpunth S, Pogoda J, Goldman J Mol Sci. 2017 Dec 29;19(1):92. doi: 10.3390/ijms19010092. PMID: MP. Evaluation of microfocused ultrasound with visualization for lifting, 29286292; PMCID: PMC5796042. tightening, and wrinkle reduction of the décolletage. J Am Acad 18. Mathew-Steiner SS, Roy S, Sen CK. Collagen in Wound Healing. Dermatol. 2013;69(6):965-971. Bioengineering (Basel). 2021 May 11;8(5):63. doi: 6. Sasaki G, Grossman J, Fabi SG, et al. Stimulation of Collagen Synthesis 10.3390/bioengineering8050063. PMID: 34064689; PMCID: in Human Skin Following Microfocused Ultrasound Therapy. PMC8151502. Presented at the ASDS 2018 Annual Meeting. 7. White WM, Makin IR, Barthe PG, Slayton MN, Gliklich RE. Selective ©2024 Merz Aesthetics GmbH. All Rights Reserved. MERZ AESTHETICS is a creation of thermal injury zones in the superficial musculoaponeurotic system using intense ultrasound therapy: a new target for noninvasive facial rejuvenation. Arch Facial Plast Surg. 2007;9(1):22-29. trademark and/or registered trademark of Merz Pharma GmbH & Co. KGaA in the EU and/or cert ain other countries. ULTHERA®, ULTHERAPY®, ULTHERAPY PRIME®, DEEPSEE®, and the squiggle logo are trademarks 8. Data on File. Current estimations indicate we will reach this milestone and/or registered trademarks of Ulthera, Inc. in the EU and/or certain other by Q4 23-24. countries. Figures/Images are not shown to size